The Parkinson’s Drug Trial: A Miracle Cure?

Below are a collection of articles, books and video relating to the first GDNF trial.

Spotlight on Darren Calder, one of the six brave volunteers who tested the safety of the delivery device.

An overview of the Bristol GDNF trial by Claire Bale, Head of Research Communications and Engagement, Parkinson’s UK.

Steve Gill, Lead Surgeon for the GDNF trial talks about his chance meeting with Tom Isaacs and how this has inspired his work with GNDF.

GDNF! What happened to me by Andy Rollins

Andy was diagnosed with Parkinson’s at the age of 47, but surely that is something that old people get? 5 years later he had a once in a lifetime chance to participate in ground breaking clinical trial to see if something called GDNF could slow, stop or reverse his Parkinson’s.

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Listening to the experiences of participants on neurosurgical trials.

Results and resources

Watch on YouTube


BBC: The full story of GDNF, with timeline

GDNF: The Ongoing Controversy
BBC archive page and further reading.


University Bristol article on the results of the trial

Pioneering trial offers hope for restoring brain cells damaged in Parkinson’s

Results from a pioneering clinical trials programme that delivered an experimental treatment directly to the brain offer hope that it may be possible to restore the cells damaged in Parkinson’s.


Parkinson’s Movement review of trial

Parkinson’s Movement strives to strengthen the position of Parkinson’s as a health priority globally. By providing a genuine, powerful tool for driving change, we can inform and influence the agenda of the wider Parkinson’s community.

Two Parkinson’s experts comment on the results of the recent GDNF trial, and discuss possible explanations for why the trial may have failed to meet its primary endpoint.